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CD137L rabbit pAb

簡要描述:SourceRabbitApplicationsWB,IF,ELISAReactivityHumanDilutionWB:1:500-1:2000

  • 產品型號:
  • 廠商性質:生產廠家
  • 更新時間:2025-09-21
  • 訪  問  量:230

詳細介紹

  • Source

    Rabbit

  • Applications

    WB,IF,ELISA

  • Reactivity

    Human

  • Dilution

    WB: 1:500 - 1:2000. IF: 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

  • Storage

    -20°C/1 year

  • Specificity

    CD137L Polyclonal Antibody detects endogenous levels of CD137L protein.

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    The antiserum was produced against synthesized peptide derived from human TNFSF9. AA range:31-80

  • Uniprot No

    P41273

  • Alternative names

    TNFSF9; Tumor necrosis factor ligand superfamily member 9; 4-1BB ligand; 4-1BBL

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    tumor necrosis factor superfamily member 9(TNFSF9) Homo sapiens The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction.[provided b

  • Other

    TNFSF9, Tumor necrosis factor ligand superfamily member 9

  • Mol.Wt (Da)

    26625

  • Concentration

    1 mg/ml

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