Cbl (phospho Tyr700) rabbit pAb

簡要描述：SourceRabbitApplicationsWB,IHC,IF,ELISAReactivityHuman,Mouse,RatDilutionWB:1:500-1:2000

產品型號：
廠商性質：生產廠家
更新時間：2025-10-15
訪問量：204

產品咨詢聯系我們

產品分類

CLASSIFICATION

Primary Antibodies

查看全部產品

相關文章ARTICLES

查看全部

詳細介紹

Source

Rabbit
Applications

WB,IHC,IF,ELISA
Reactivity

Human,Mouse,Rat
Dilution

WB: 1:500 - 1:2000. IHC: 1:100 - 1:300. IF: 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

Phospho-Cbl (Y700) Polyclonal Antibody detects endogenous levels of Cbl protein only when phosphorylated at Y700.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from human CBL around the phosphorylation site of Tyr700. AA range:666-715
Uniprot No

P22681
Alternative names

CBL; CBL2; RNF55; E3 ubiquitin-protein ligase CBL; Casitas B-lineage lymphoma proto-oncogene; Proto-oncogene c-Cbl; RING finger protein 55; Signal transduction protein CBL
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

Cbl proto-oncogene(CBL) Homo sapiens This gene is a proto-oncogene that encodes a RING finger E3 ubiquitin ligase. The encoded protein is one of the enzymes required for targeting substrates for degradation by the proteasome. This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes (E2) to specific substrates. This protein also contains an N-terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine-phosphorylated substrates and target them for proteasome degradation. As such it functions as a negative regulator of many signal transduction pathways. This gene has been found to be mutated or translocated in many cancers including acute myeloid leukaemia, and expansion of CGG repeats in the 5' UTR has been associated with Jacobsen syndrome. Mutations in this gene are also the cause of Noonan syndrome-like disorder. [provided by RefSeq, Jul 2016],
Other

CBL, E3 ubiquitin-protein ligase CBL
Mol.Wt (Da)

99647
Concentration

1 mg/ml

Product	Reactivity	Applications	Conjugation	Catalog	Images

產品咨詢

亚洲国产精品久久久久久高潮_午夜福利在线观看丝袜_国产午夜手机精彩视频_精品久久久蜜桃嫩草av_亚洲国产精品五月天久久久_内射人妻精品_亚洲精品无码中字_亚州色一区_香蕉免费伦理电影网站_日本免费精品一区二区

Cbl (phospho Tyr700) rabbit pAb

Source

Applications

Reactivity

Dilution

Storage

Specificity

Source/Purification

Immunogen

Uniprot No

Alternative names

Form

Clonality

Isotype

Background

Other

Mol.Wt (Da)

Concentration

留言框

產品：

您的單位：

您的姓名：

聯系電話：

常用郵箱：

省份：

詳細地址：

補充說明：

驗證碼：